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ITGA4 Antibody

APR16913G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR16913G		100 μl / ￥5450

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ITGA4 Antibody

品牌	Leading Biology	货号	APR16913G
产品分类	Monoclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGA4 antibody.
分子量	115kDa
细胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Mouse
种属反应性	Human
克隆号	5C4
亚型	IgG1
通用名	CD49D
基因ID	3676
UniProt ID	P13612
功能	Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
形式	Liquid. In PBS containing 0.02% sodium azide.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, FC, E
稀释方法	E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400
别名	Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, CD49d, ITGA4, CD49D
图像	Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using ITGA4 mAb against human ITGA4 (AA: 926-978) recombinant protein. (Expected MW is 31.7 kDa) Figure 2: Western blot analysis using ITGA4 mouse mAb against K562(1) and Jurkat (2) cell lysate.
说明书	Product Datasheet Protocol
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