全部产品分类
品牌 |
Leading Biology | 货号 |
APR15332G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD133 antibody.
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分子量 |
133kDa
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细胞定位 |
Antigen Cellular Localization:
Apical cell membrane; Multi- pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein Cell projection, cilium, photoreceptor outer segment. Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Note=Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
3F10
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亚型 |
IgG1
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通用名 |
PROML1
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基因ID |
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UniProt ID |
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功能 |
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, FC, E
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稀释方法 |
E~~1/10000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
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别名 |
Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1
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图像 |
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说明书 |
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数量 |
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