全部产品分类
品牌 |
Leading Biology | 货号 |
APR08467G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MNK / ATP7A antibody (clone S60-4).
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分子量 |
163kDa
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Cycles constitutively between the trans- Golgi network (TGN) and the plasma membrane. Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels Isoform 5: Endoplasmic reticulum.
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Detects ~180kDa in rat brainmembrane preparations.
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克隆号 |
S60-4
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通用名 |
MC1, MNK
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基因ID |
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UniProt ID |
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功能 |
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
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总结 |
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IP
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稀释方法 |
IHC-P (10 μg/ml)
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别名 |
Copper-transporting ATPase 1, 3.6.3.54, Copper pump 1, Menkes disease-associated protein, ATP7A, MC1, MNK
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图像 |
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说明书 |
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数量 |
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