全部产品分类
品牌 |
Leading Biology | 货号 |
APR10743G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VLDLR antibody (clone 1H10).
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分子量 |
96kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Binds to an epitope on the C-terminus of the ligand binding domain (aa191-355) of VLDL receptor and blocks apoE4 binding.
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克隆号 |
1H10
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基因ID |
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UniProt ID |
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功能 |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
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总结 |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
IHC-P (1:50)
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别名 |
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
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图像 |
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说明书 |
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数量 |
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