全部产品分类
品牌 |
Leading Biology | 货号 |
APR13810G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRPC4 antibody (aa930-947, clone S77-15).
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分子量 |
112kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Enhanced insertion into the cell membrane after activation of the EGF receptor
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Detects ~110 kD protein.
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克隆号 |
S77-15
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基因ID |
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UniProt ID |
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功能 |
Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.
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总结 |
Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, ICC, IP
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稀释方法 |
ICC (0.1-1 μg/ml), IHC-P (1:50), IP (1-10 μg/ml), WB (1-10 μg/ml) ,
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别名 |
Short transient receptor potential channel 4, TrpC4, Trp-related protein 4, hTrp-4, hTrp4, TRPC4
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图像 |
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说明书 |
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数量 |
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