全部产品分类
品牌 |
Leading Biology | 货号 |
AMR09784G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RTN3 / Reticulon 3 antibody (clone 10A8).
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分子量 |
113kDa
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Human RTN3
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克隆号 |
10A8
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通用名 |
ASYIP, NSPL2
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基因ID |
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UniProt ID |
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功能 |
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.
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总结 |
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, E
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稀释方法 |
ELISA (1:10000), IHC-P (1:200),
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别名 |
Reticulon-3, Homolog of ASY protein, HAP, Neuroendocrine-specific protein-like 2, NSP-like protein 2, Neuroendocrine-specific protein-like II, NSP-like protein II, NSPLII, RTN3, ASYIP, NSPL2
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图像 |
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说明书 |
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数量 |
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