品牌 |
Leading Biology | 货号 |
APR17195G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LIM Protein / LPP antibody.
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分子量 |
66kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Purified truncated recombinant LPP-His is expressed in E. coli strain BL21 (DE3).
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基因ID |
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UniProt ID |
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功能 |
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
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总结 |
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000) ,
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别名 |
Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP
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图像 |
Western blot using LPP mouse monoclonal antibody against HeLa (1), NIH/3T3 (2), COS (3), Caki...
Confocal immunofluorescence of COS cells using LPP mouse monoclonal antibody (green).
Confocal immunofluorescence of HeLa cells using LPP mouse monoclonal antibody (green). |
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说明书 |
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数量 |
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