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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > NKIRAS1 Antibody (aa96-113, clone 184C278)

NKIRAS1 Antibody (aa96-113, clone 184C278)

货号 货期 规格 / 价格 询价
APR17577G 50 μg / ¥4950

NKIRAS1 Antibody (aa96-113, clone 184C278)

品牌

Leading Biology

货号

APR17577G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NKIRAS1 antibody (aa96-113, clone 184C278).

分子量

22kDa

细胞定位

Antigen Cellular Localization: Cytoplasm.

宿主

Mouse

种属反应性

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Goat, Horse, Dog

靶点

A synthetic peptide containing amino acid residues 96-113 of human kB-Ras1.

克隆号

184C278

通用名

KBRAS1

基因ID

UniProt ID

功能

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

总结

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P

稀释方法

IHC-P (5 μg/ml), WB (0.5-1 μg/ml),

别名

NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1, NKIRAS1, KBRAS1

图像

Anti-NKIRAS1 antibody IHC of human breast.

说明书

数量

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