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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > ITA6 Antibody

ITA6 Antibody

货号 货期 规格 / 价格 询价
APR17796G 100 μl / ¥4950

ITA6 Antibody

品牌

Leading Biology

货号

APR17796G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITA6 antibody.

分子量

H=119,124,107,122 KDa

细胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Cell membrane; Lipid-anchor

宿主

Mouse

种属反应性

Human

免疫原

324-640 aa

靶点

ITA6 recombinant protein is used to produce this monoclonal antibody.

基因ID

UniProt ID

功能

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.

总结

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

形式

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

FC, IF, IHC-P, WB

稀释方法

WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50 FC~~1:10~50

别名

Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6, Alpha6p, ITGA6

图像

All lanes : Anti-ITA6 Antibody at 1:1000 dilution Lane 1: SW480 whole cell lysates Lane 2: human placenta lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 119 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

ITA6 Monoclonal Antibody (Cat. APR17796G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ITA6 Monoclonal Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of ITA6 Antibody ( APR17796G) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).

说明书

数量

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