品牌 |
Leading Biology | 货号 |
APR10993G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATXN1 antibody.
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分子量 |
87kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Colocalizes with USP7 in the nucleus
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
2F5
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亚型 |
IgG1
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通用名 |
ATX1, SCA1
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基因ID |
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UniProt ID |
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功能 |
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
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别名 |
Ataxin-1, Spinocerebellar ataxia type 1 protein, ATXN1, ATX1, SCA1
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图像 |
Figure 1: Western blot analysis using ATXN1 mAb against HEK293 (1) and ATXN1(AA: 645-815)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) using ATXN1 mouse mAb with DAB staining.
Figure 3: Immunofluorescence analysis of NTERA-2 cells using ATXN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. |
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说明书 |
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数量 |
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