品牌 |
Leading Biology | 货号 |
APR10172G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOCS3 antibody (monoclonal) (M02).
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分子量 |
24770 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
SOCS3 (AAH60858, 1 a.a. ~ 225 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
1.00E+05
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亚型 |
IgG2b Kappa
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基因ID |
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UniProt ID |
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总结 |
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, IF, E
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别名 |
Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3, SOCS3, CIS3, SSI3
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图像 |
Immunoperoxidase of monoclonal antibody to SOCS3 on formalin-fixed paraffin-embedded human colon. [antibody concentration 1.5 ug/ml]
Immunofluorescence of monoclonal antibody to SOCS3 on HeLa cell . [antibody concentration 10 ug/ml]
Detection limit for recombinant GST tagged SOCS3 is approximately 3ng/ml as a capture antibody. |
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说明书 |
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数量 |
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