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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > SMAD7 Antibody (monoclonal) (M05)

SMAD7 Antibody (monoclonal) (M05)

货号 货期 规格 / 价格 询价
AMM07898G 100 μg / ¥4950

SMAD7 Antibody (monoclonal) (M05)

品牌

Leading Biology

货号

AMM07898G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMAD7 antibody (monoclonal) (M05).

分子量

46426 Da

宿主

Mouse

种属反应性

Human

靶点

SMAD7 (NP_005895, 160 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆号

2G6

亚型

IgG2a Kappa

基因ID

UniProt ID

总结

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

形式

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

稀释方法

WB~~1:500~1000

别名

Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7, SMAD7, MADH7, MADH8

图像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.85 KDa) .

SMAD7 monoclonal antibody (M05), clone 2G6. Western Blot analysis of SMAD7 expression in MCF-7.

说明书

数量

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