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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > GSTA1 Antibody (monoclonal) (M08)

GSTA1 Antibody (monoclonal) (M08)

货号 货期 规格 / 价格 询价
AMM05233G 100 μg / ¥4950

GSTA1 Antibody (monoclonal) (M08)

品牌

Leading Biology

货号

AMM05233G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GSTA1 antibody (monoclonal) (M08).

分子量

25631 Da

宿主

mouse

种属反应性

Human

靶点

GSTA1 (AAH53578.1, 1 a.a. ~ 222 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆号

1F9

亚型

IgG1 kappa

基因ID

UniProt ID

总结

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

形式

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:500~1000

别名

Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1

图像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (50.16 KDa) .

GSTA1 monoclonal antibody (M08), clone 1F9. Western Blot analysis of GSTA1 expression in human liver.

Western Blot analysis of GSTA1 expression in transfected 293T cell line by GSTA1 monoclonal antibody (M08), clone 1F9. Lane 1: GSTA1 transfected lysate(26 KDa). Lane 2: Non-transfected lysate.

说明书

数量

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