品牌 |
Leading Biology | 货号 |
AMM04830G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GNB3 antibody (monoclonal) (M01).
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分子量 |
37221 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
GNB3 (AAH02454, 1 a.a. ~ 340 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
M1-1-1D5
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亚型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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总结 |
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF
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稀释方法 |
WB~~1:500~1000
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别名 |
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Transducin beta chain 3, GNB3
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图像 |
GNB3 monoclonal antibody (M01), clone M1-1-1D5 Western Blot analysis of GNB3 expression in HepG2 ( Cat L019V1 ).
Immunofluorescence of monoclonal antibody to GNB3 on HepG2 cell. [antibody concentration 10 ug/ml] |
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说明书 |
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数量 |
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