品牌 |
Leading Biology | 货号 |
APG03264G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EFNA5 antibody (monoclonal) (M01).
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分子量 |
26297 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
EFNA5 (NP_001953, 114 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
1F12
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亚型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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总结 |
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:500~1000
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别名 |
Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7, EFNA5, EPLG7, LERK7
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图像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .
EFNA5 monoclonal antibody (M01), clone 1F12. Western Blot analysis of EFNA5 expression in IMR-32.
Detection limit for recombinant GST tagged EFNA5 is approximately 0.03ng/ml as a capture antibody. |
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说明书 |
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数量 |
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