全部产品分类
品牌 |
Leading Biology | 货号 |
APR15128G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAIAP2L1 antibody (monoclonal) (M01).
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分子量 |
56883 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
BAIAP2L1 (NP_061330, 398 a.a. ~ 511 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
2A4
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亚型 |
IgG1 Kappa
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基因ID |
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UniProt ID |
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总结 |
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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稀释方法 |
WB~~1:500~1000
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别名 |
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate, BAIAP2L1, IRTKS
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图像 |
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说明书 |
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数量 |
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