全部产品分类
品牌 |
Leading Biology | 货号 |
APR11373G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality alpha Synuclein antibody.
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分子量 |
15 KDa
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Full length human alpha synuclein expressed in E. Coli.
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克隆号 |
3H9
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亚型 |
IgG1
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基因ID |
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UniProt ID |
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总结 |
Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Early onset Parkinson's disease may be caused by a duplication or triplication of one of the alpha synuclein genes (Chartier-Harlin MC et al., 2004 and Singleton, AB et al., 2005). Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS).
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形式 |
Mouse ascites fluid.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IF, WB
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稀释方法 |
WB~~ 1:1000
IF~~ 1:500
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别名 |
Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1
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图像 |
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说明书 |
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数量 |
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