品牌 |
Leading Biology | 货号 |
AMM06633G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Neurofilament H (NF-H) antibody.
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分子量 |
200 KDa
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宿主 |
Mouse
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种属反应性 |
Rat
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靶点 |
Purified bovine NF-H.
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克隆号 |
NAP4
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亚型 |
IgG1
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基因ID |
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UniProt ID |
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总结 |
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3).
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形式 |
Unpurified mouse ascites fluid.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IF, WB
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稀释方法 |
WB~~ 1:5000
IF~~ 1:500
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别名 |
Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH
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图像 |
Western blot of rat cortex lysate showing specific immunolabeling of the ~ 200k NF-H protein.
Immunostaining of human cerebellar cortex showing labeling of NF-H (brown) in basket cell axons surrounding the large Purkinje neurons. |
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说明书 |
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数量 |
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