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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > LH-beta (Luteinizing Hormone-beta) Antibody - Without BSA and Azide

LH-beta (Luteinizing Hormone-beta) Antibody - Without BSA and Azide

货号 货期 规格 / 价格 询价
APR07430G 100 μg / ¥4950

LH-beta (Luteinizing Hormone-beta) Antibody - Without BSA and Azide

品牌

Leading Biology

货号

APR07430G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LH-beta (Luteinizing Hormone-beta) antibody - Without BSA and Azide.

分子量

22kDa

细胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

种属反应性

Human

克隆号

LHb/1214

亚型

Mouse / IgG1, kappa

基因ID

UniProt ID

功能

Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

总结

Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.?LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC, IF, FC

别名

Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta, LHB

图像

Formalin-fixed, paraffin-embedded human Pituitary stained with LH-beta Monoclonal Antibody (LHb/1214).

说明书

数量

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