> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody - Without BSA and Azide品牌 |
Leading Biology | 货号 |
APR07423G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Insulin / IRDN (beta-Cell & Insulinoma Marker) antibody - Without BSA and Azide.
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分子量 |
6kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat, Pig, Cow
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克隆号 |
IRDN/794
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亚型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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总结 |
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, IF, FC
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别名 |
Insulin, Insulin B chain, Insulin A chain, INS
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图像 |
Formalin-fixed, paraffin-embedded human Pancreas stained with Insulin Monoclonal Antibody (IRDN/794).
Formalin-fixed, paraffin-embedded Rat Pancreas stained with Insulin Monoclonal Antibody (IRDN/794). |
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说明书 |
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数量 |
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