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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody品牌 |
Leading Biology | 货号 |
APR14601G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) antibody.
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分子量 |
52-67kDa
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog
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克隆号 |
AE-3
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亚型 |
Mouse / IgG1, kappa
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通用名 |
KRT2B, KRT2P
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基因ID |
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UniProt ID |
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功能 |
Probably contributes to terminal cornification.
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总结 |
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IF, FC
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别名 |
Keratin, type II cytoskeletal 2 oral, Cytokeratin-2P, CK-2P, K2P, Keratin-76, K76, Type-II keratin Kb9, KRT76, KRT2B, KRT2P
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图像 |
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说明书 |
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数量 |
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