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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Parathyroid Hormone (PTH) (C-Terminal) Antibody

Parathyroid Hormone (PTH) (C-Terminal) Antibody

货号 货期 规格 / 价格 询价
APR14691G 7 ml / ¥4950

Parathyroid Hormone (PTH) (C-Terminal) Antibody

品牌

Leading Biology

货号

APR14691G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Parathyroid Hormone (PTH) (C-Terminal) antibody.

分子量

9kDa

细胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

种属反应性

Human

克隆号

PTH/1174

亚型

Mouse / IgG2b, kappa

基因ID

UniProt ID

功能

PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

总结

Epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.?It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

形式

Liquid. In PBS containing 0.02% sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC, IF, FC

别名

Parathyroid hormone, PTH, Parathormone, Parathyrin, PTH

图像

Formalin-fixed, paraffin-embedded human Parathyroid stained with PTH Monoclonal Antibody (PTH/1174).

Formalin-fixed, paraffin-embedded human Parathyroid stained with PTH Monoclonal Antibody (PTH/1174).

说明书

数量

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