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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody品牌 |
Leading Biology | 货号 |
APR14673G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 antibody.
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分子量 |
130kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat, Rabbit, Dog
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克隆号 |
CDH16/1071
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亚型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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总结 |
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.?Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, IF, FC
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别名 |
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
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图像 |
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说明书 |
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数量 |
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