品牌 |
Leading Biology | 货号 |
APR13642G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Syntenin antibody.
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分子量 |
32 KDa
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细胞定位 |
Antigen Cellular Localization:
Cell junction, focal adhesion. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Melanosome. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum Colocalized with actin stress fibers. Also found in the nucleus Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Mouse
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种属反应性 |
Human
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通用名 |
MDA9, SYCL
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基因ID |
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UniProt ID |
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功能 |
Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
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总结 |
Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
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形式 |
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~1:1000
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别名 |
MDA-9;MDA9;Melanoma differentiation-associated protein 9;Pro-TGF-alpha cytoplasmic domain-interacting protein 18;Scaffold protein Pbp1;SDCB1_HUMAN;Sdcbp;SDCBP;ST1;SYCL; Syndecan binding protein (syntenin);Syndecan binding protein 1;Syndecan-binding protein 1;Syntenin 1;Syntenin-1;TACIP18.
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图像 |
Western blot detection of Syntenin in HelaNE and Hela cell lysates using Syntenin mouse mAb (1:1000 diluted).Predicted band size:32KDa.Observed band size:32KDa. |
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说明书 |
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数量 |
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