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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > SOD2 Antibody

SOD2 Antibody

货号 货期 规格 / 价格 询价
APR10198G 100 μl / ¥4950

SOD2 Antibody

品牌

Leading Biology

货号

APR10198G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOD2 antibody.

分子量

24722 Da

细胞定位

Antigen Cellular Localization: Mitochondrion matrix.

宿主

Mouse

种属反应性

Human

靶点

Purified His-tagged SOD protein(Fragment) was used to produced this monoclonal antibody.

克隆号

37CT127.5.11.6

亚型

IgG1κ

基因ID

UniProt ID

功能

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

总结

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

形式

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC-P, WB, E

稀释方法

WB~~1:2000 IHC-P~~1:10~50

别名

Superoxide dismutase [Mn], mitochondrial, SOD2

图像

All lanes : Anti-SD Antibody at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: human brain lysates Lane 3: human heart lysates Lane 4: human liver lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 Monoclonal Antibody (Cat. APR10198G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot analysis of anti-SOD2 Monoclonal Antibody (Cat. APR10198G) by SOD2-GST fusion protein (GST MW=26 kD. SOD2-GST fusion protein (arrow) was detected using the purified Mab. (1:2000)

说明书

数量

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