品牌 |
Leading Biology | 货号 |
APR17284G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAP3K13 (LZK) antibody (C-term).
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分子量 |
108296 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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宿主 |
Mouse
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种属反应性 |
Human
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免疫原 |
52-305 aa
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靶点 |
Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody.
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克隆号 |
810CT26.6.1.1
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亚型 |
IgM
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基因ID |
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UniProt ID |
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功能 |
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
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总结 |
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
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形式 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, E
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稀释方法 |
IF~~1:100
WB~~1:1000
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别名 |
Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (HGNC:6852)
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图像 |
Fluorescent image of NCI-H460 cells stained with MAP3K13 (LZK) Antibody (N-term)( AM2234B). AM2234B was diluted at 1:100 dilution. An Alexa Fluor? 488-conjugated goat anti-mouse lgM at 1:400 dilution was used as the secondary antibody (green). DAPI was used to stain the cell nuclear (blue).
Fluorescent image of NCI-H460 cells stained with MAP3K13 (LZK) Antibody (N-term)( AM2234B). AM2234B was diluted at 1:100 dilution. An Alexa Fluor? 488-conjugated goat anti-mouse lgM at 1:400 dilution was used as the secondary antibody (green).
Fluorescent image of NCI-H460 cells stained with MAP3K13 (LZK) Antibody (N-term)( AM2234B). AM2234B was diluted at 1:100 dilution. An Alexa Fluor? 488-conjugated goat anti-mouse lgM at 1:400 dilution was used as the secondary antibody (green). DAPI was used to stain the cell nuclear (blue). Cytoplasmic actin was counterstained with Alexa Fluor? 555 conjugated with Phalloidin (red). |
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说明书 |
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数量 |
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