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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > CYP1A1 Antibody (C-term) (Ascites)

CYP1A1 Antibody (C-term) (Ascites)

货号 货期 规格 / 价格 询价
APG02870G 0.1 ml / ¥4950

CYP1A1 Antibody (C-term) (Ascites)

品牌

Leading Biology

货号

APG02870G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP1A1 antibody (C-term) (Ascites).

分子量

58165 Da

细胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein

宿主

Mouse

种属反应性

Human

免疫原

377-405 aa

靶点

This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.

克隆号

655CT6.1.2

亚型

IgG1

基因ID

UniProt ID

功能

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

总结

This gene, CYP1A1, encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by some polycyclic aromatic hydrocarbons(PAHs), some of which are found in cigarette smoke. The enzyme'sendogenous substrate is unknown; however, it is able to metabolizesome PAHs to carcinogenic intermediates. The gene has beenassociated with lung cancer risk. A related family member, CYP1A2,is located approximately 25 kb away from CYP1A1 on chromosome 15.

形式

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:500~4000

别名

Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, CYP1A1

图像

CYP1A1 Antibody (C-term)(Ascites)(Cat. APG02870G) western blot analysis in 293 cell line lysates (35μg/lane).This demonstrates the CYP1A1 antibody detected the CYP1A1 protein (arrow).

说明书

数量

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