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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > ADA Antibody (C-term) (Ascites)

ADA Antibody (C-term) (Ascites)

货号 货期 规格 / 价格 询价
APG01546G 0.1 ml / ¥4950

ADA Antibody (C-term) (Ascites)

品牌

Leading Biology

货号

APG01546G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADA antibody (C-term) (Ascites).

分子量

40764 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion

宿主

Mouse

种属反应性

Human

免疫原

287-314 aa

靶点

This ADA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA.

克隆号

608CT2.1.3

亚型

IgG1

通用名

ADA1

基因ID

UniProt ID

功能

Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion.

总结

This gene encodes an enzyme that catalyzes the hydrolysisof adenosine to inosine. Various mutations have been described forthis gene and have been linked to human diseases. Deficiency inthis enzyme causes a form of severe combined immunodeficiencydisease (SCID), in which there is dysfunction of both B and Tlymphocytes with impaired cellular immunity and decreasedproduction of immunoglobulins, whereas elevated levels of thisenzyme have been associated with congenital hemolytic anemia.

形式

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:500~8000

别名

Adenosine deaminase, Adenosine aminohydrolase, ADA, ADA1

图像

ADA Antibody (C-term)(Ascites)(Cat. APG01546G) western blot analysis in Jurkat cell line lysates (35μg/lane).This demonstrates the ADA antibody detected the ADA protein (arrow).

说明书

数量

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