全部产品分类
品牌 |
Leading Biology | 货号 |
APR08342G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAP4K3 antibody (ascites).
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分子量 |
101316 Da
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
This MAP4K3 monoclonal antibody is generated from mouse immunized with MAP4K3 recombinant protein.
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克隆号 |
219CT8.3.1
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亚型 |
IgM,k
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通用名 |
RAB8IPL1
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基因ID |
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UniProt ID |
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功能 |
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
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总结 |
This gene encodes a member of the Ste20 family ofserine/threonine protein kinases. The protein belongs to thesubfamily that consists of members, such as germinal center kinase(GCK), that are characterized by an N-terminal catalytic domain andC-terminal regulatory domain. The kinase activity of the encodedprotein can be stimulated by UV radiation and tumor necrosisfactor-alpha. The protein specifically activates the c-JunN-terminal kinase (JNK) signaling pathway. Evidence suggests thatit functions upstream of mitogen-activated protein kinase kinasekinase 1 (MEKK1). This gene previously was referred to asRAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamedmitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000~8000
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别名 |
Mitogen-activated protein kinase kinase kinase kinase 3, Germinal center kinase-related protein kinase, GLK, MAPK/ERK kinase kinase kinase 3, MEK kinase kinase 3, MEKKK 3, MAP4K3, RAB8IPL1
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图像 |
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说明书 |
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数量 |
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