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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

货号 货期 规格 / 价格 询价
APR07352G 50 μg / ¥3950

GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

品牌

Leading Biology

货号

APR07352G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) antibody - With BSA and Azide.

分子量

94kDa

细胞定位

Antigen Cellular Localization: Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

宿主

Rat

种属反应性

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Cow, Sheep, Xenopus, Horse, Guinea Pig, Dog

克隆号

SPM249

亚型

Rat / IgG2a, kappa

通用名

GRP94, TRA1

基因ID

UniProt ID

功能

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.

总结

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, FC

别名

Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1

图像

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with GRP94 Monoclonal Antibody (SPM249).

说明书

数量

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