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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Milk Fat Globule (Breast Epithelial Marker) Antibody - With BSA and Azide

Milk Fat Globule (Breast Epithelial Marker) Antibody - With BSA and Azide

货号 货期 规格 / 价格 询价
AMM04410G 50 μg / ¥3950

Milk Fat Globule (Breast Epithelial Marker) Antibody - With BSA and Azide

品牌

Leading Biology

货号

AMM04410G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Milk Fat Globule (Breast Epithelial Marker) antibody - With BSA and Azide.

分子量

45kDa

细胞定位

Antigen Cellular Localization: Membrane; Peripheral membrane protein Secreted

宿主

Mouse

种属反应性

Human

克隆号

SPM291

亚型

Mouse / IgG1, kappa

基因ID

UniProt ID

功能

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

总结

Recognizes a protein of 40-45kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC, IF, FC

别名

Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8

图像

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with Milk Fat Globule Monoclonal Antibody (SPM291)

说明书

数量

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