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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody - With BSA and Azide

Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody - With BSA and Azide

货号 货期 规格 / 价格 询价
APR07412G 50 μg / ¥3950

Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody - With BSA and Azide

品牌

Leading Biology

货号

APR07412G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Insulin / IRDN (beta-Cell & Insulinoma Marker) antibody - With BSA and Azide.

分子量

6kDa

细胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

种属反应性

Human, Mouse, Rabbit, Pig, Cow

克隆号

IRDN/805

亚型

Mouse / IgG1, kappa

基因ID

UniProt ID

功能

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

总结

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC, IF, FC

别名

Insulin, Insulin B chain, Insulin A chain, INS

图像

Formalin-fixed, paraffin-embedded human Pancreas stained with Insulin Monoclonal Antibody (IRDN/805).

说明书

数量

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