> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant品牌 |
Leading Biology | 货号 |
APR07207G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMACR / p504S (Prostate Cancer Marker) antibody - Culture Supernatant .
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分子量 |
54kDa
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细胞定位 |
Antigen Cellular Localization:
Peroxisome. Mitochondrion
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Full length human recombinant AMACR protein
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克隆号 |
13H4
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.
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总结 |
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
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形式 |
0.5 ml of Culture Supernatant with azide
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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别名 |
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
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图像 |
Formalin-fixed, paraffin-embedded human prostate carcinoma (10X) stained with AMACR / p504S Rabbit MAb (13H4).
Formalin-fixed, paraffin-embedded human prostate carcinoma (20X) stained with AMACR / p504S Rabbit MAb (13H4). |
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说明书 |
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数量 |
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