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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

货号 货期 规格 / 价格 询价
APR07207G 0.1 ml / ¥3950

AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant

品牌

Leading Biology

货号

APR07207G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMACR / p504S (Prostate Cancer Marker) antibody - Culture Supernatant .

分子量

54kDa

细胞定位

Antigen Cellular Localization: Peroxisome. Mitochondrion

宿主

Rabbit

种属反应性

Human

靶点

Full length human recombinant AMACR protein

克隆号

13H4

亚型

IgG

基因ID

UniProt ID

功能

Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.

总结

This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

形式

0.5 ml of Culture Supernatant with azide

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC

别名

Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR

图像

Formalin-fixed, paraffin-embedded human prostate carcinoma (10X) stained with AMACR / p504S Rabbit MAb (13H4).

Formalin-fixed, paraffin-embedded human prostate carcinoma (20X) stained with AMACR / p504S Rabbit MAb (13H4).

说明书

数量

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