全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07636G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
|
产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ROR2 antibody.
|
||
分子量 |
104757 Da
|
||
细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
|
||
宿主 |
Rabbit
|
||
种属反应性 |
Human
|
||
靶点 |
A synthetic peptide corresponding to residues of human ROR2 was used as an immunogen.
|
||
克隆号 |
EPR3779
|
||
通用名 |
NTRKR2
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.
|
||
总结 |
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a tyrosine protein kinase receptor which is required for cartilage and growth plate development. As a member of the receptor protein kinases (RTKs) family, ROR2 is commonly found in embryonic kidney, but its function has not been fully understood. ROR2 has been linked to embryonic development due its involvement in WNT signaling pathway. Additionally, ROR2 has been shown to be critical for the formation of skeleton, heart, and genitals. Specifically, ROR2 phosphorylates 14-3-3 protein beta/alpha which leads to induction of osterogenesis and bone formation (2). A mutation in ROR2 is commonly seen in Robinow syndrome and autosomal dominant brachydactyly B disorders (3).
|
||
形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
|
||
储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
应用 |
WB, FC
|
||
稀释方法 |
WB~~1:500
FC~~1:10~100
|
||
别名 |
Tyrosine-protein kinase transmembrane receptor ROR2, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2
|
||
图像 |
|
||
说明书 |
|||
数量 |
|
||
| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Leading Biology | APG01369G | VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide | 100 μg | Monoclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 2 | Leading Biology | AMM07627G | RIN2 Antibody (monoclonal) (M01) | 100 μg | Monoclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 3 | Leading Biology | APR15980G | FGG Antibody | 100 μl | Monoclonal Antibodies |
|
￥5450.00 | 订购 询价 | ||
| 4 | Leading Biology | AMM05161G | GOB5 / CLCA1 Antibody (clone 1C4) | 50 μg | Monoclonal Antibodies |
|
￥5450.00 | 订购 询价 | ||
| 5 | Leading Biology | APR11118G | HIV-1 p24 Antibody [7F4] (biotin) | 0.1 mg | Monoclonal Antibodies |
|
￥6950.00 | 订购 询价 | ||
| 6 | Leading Biology | APR17667G | ORAI1 Antibody [3F6H5] | 0.1 mg | Monoclonal Antibodies |
|
￥6950.00 | 订购 询价 |
微信扫描二维码，随时随地与小诺亲密接触，精彩活动，劲爆优惠，触手可得！
销售-华东区