全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07508G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
|
产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Radixin antibody.
|
||
分子量 |
68564 Da
|
||
细胞定位 |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively
|
||
宿主 |
Rabbit
|
||
种属反应性 |
Human, Mouse, Rat
|
||
靶点 |
A synthetic peptide corresponding to residues near the N-terminus of human Radixin was used as an immunogen.
|
||
克隆号 |
EP1862Y
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
|
||
总结 |
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. Recent cloning of the murine and porcine radixin cDNAs revealed a protein highly homologous to ezrin and moesin (1). The ezrin-radixin-moesin (ERM) family of proteins crosslink actin filaments and integral membrane proteins. Radixin (encoded by Rdx) is the dominant ERM protein in the liver of wildtype mice and is concentrated at bile canalicular membranes (BCMs). Findings indicate that radixin is required for secretion of conjugated bilirubin through its support of Mrp2 localization at BCMs (2). Proteins of the ezrin-radixin-moesin family are ubiquitous constituents of the submembrane cortex, especially in epithelial cells. Radixin is thus a prominent constituent of stereocilia, where it may participate in anchoring the pointed ends of actin filaments to the membrane (3).
|
||
形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
|
||
储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
应用 |
WB, IHC
|
||
稀释方法 |
WB~~1:1000~5000
IHC~~1:100~250
|
||
别名 |
Radixin, RDX
|
||
图像 |
|
||
说明书 |
|||
数量 |
|
||
| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Leading Biology | APG01369G | VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide | 100 μg | Monoclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 2 | Leading Biology | AMM07627G | RIN2 Antibody (monoclonal) (M01) | 100 μg | Monoclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 3 | Leading Biology | APR15980G | FGG Antibody | 100 μl | Monoclonal Antibodies |
|
￥5450.00 | 订购 询价 | ||
| 4 | Leading Biology | AMM05161G | GOB5 / CLCA1 Antibody (clone 1C4) | 50 μg | Monoclonal Antibodies |
|
￥5450.00 | 订购 询价 | ||
| 5 | Leading Biology | APR11118G | HIV-1 p24 Antibody [7F4] (biotin) | 0.1 mg | Monoclonal Antibodies |
|
￥6950.00 | 订购 询价 | ||
| 6 | Leading Biology | APR17667G | ORAI1 Antibody [3F6H5] | 0.1 mg | Monoclonal Antibodies |
|
￥6950.00 | 订购 询价 |
微信扫描二维码，随时随地与小诺亲密接触，精彩活动，劲爆优惠，触手可得！
销售-华东区