全部产品分类
品牌 |
Leading Biology | 货号 |
APR09051G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Peroxiredoxin-6 antibody.
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分子量 |
25035 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
A synthetic peptide corresponding to residues of human Peroxiredoxin 6 was used as an immunogen.
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克隆号 |
EPR3754
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通用名 |
AOP2, KIAA0106
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基因ID |
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UniProt ID |
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功能 |
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
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总结 |
Peroxiredoxins (Prx) are a family of ubiquitous antioxidant enzymes which regulates cytokine-induced peroxide levels and mediates signal transduction in various mammalian cells. Prx family members have been linked to cell proliferation, differentiation, and apoptosis (1). Peroxiredoxin 6 (Prdx6) is only mammalian 1-Cys member of the peroxiredoxin family and it is expressed in all major organs, with particularly high expression in lung. Prdx6 is considered antioxidant enzyme and has a major role in lung phospholipid metabolism. Specifically, Prdx6 might be involved in antioxidant defense by facilitating repair of damaged cell membranes via reduction of peroxidized phospholipids and alterations of lung surfactant phospholipid synthesis and turnover (2).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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稀释方法 |
WB~~1:1000~5000
IHC~~1:250~500
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别名 |
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106
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图像 |
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说明书 |
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数量 |
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