品牌 |
Leading Biology | 货号 |
APR07137G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Myoglobin antibody.
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分子量 |
17184 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
A synthetic peptide corresponding to residues on the C-terminus of human myglobin was used as an immunogen.
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克隆号 |
EP3081Y
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基因ID |
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UniProt ID |
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功能 |
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
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总结 |
Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration during periods of high physiological demand (1). Myoglobin may serve a variety of functions in muscular oxygen supply, such as oxygen storage, facilitated O(2) diffusion, and myoglobin-mediated oxidative phosphorylation. Disruption of myoglobin results in the activation of multiple compensatory mechanisms that steepen the pO(2) gradient and reduce the diffusion path length for O(2) between capillary and the mitochondria (2).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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稀释方法 |
WB~~1:1000~5000
IHC~~1:250~500
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别名 |
Myoglobin, MB
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图像 |
A. Western blot analysis on (A) human muscle (B) mouse muscle and (C) rat muscle tissue lysate using anti-myglobin RabMAb (Cat. APR07137G), dilution 1:5000.
B. Immunohistochemical analysis of paraffin-embedded human heart muscles using anti-Myoglobin RabMAb (Cat. APR07137G). |
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说明书 |
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数量 |
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