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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > HNRPUL1 Antibody

HNRPUL1 Antibody

货号 货期 规格 / 价格 询价
AMM05387G 100 μl / ¥5450

HNRPUL1 Antibody

品牌

Leading Biology

货号

AMM05387G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRPUL1 antibody.

分子量

95739 Da

细胞定位

Antigen Cellular Localization: Nucleus

宿主

Rabbit

种属反应性

Human

靶点

A synthetic peptide corresponding to residues on the C-terminus of human HNRPUL1 was used as an immunogen.

克隆号

EP2633Y

通用名

E1BAP5, HNRPUL1

基因ID

UniProt ID

功能

Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.

总结

Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRPUL1) is a nuclear RNA binding protein belonging to hnRNP family.(1) HNRPUL1 interacts with adenovirus type 5 (Ad5) E1B-55 kDa, BRD7, HRMT1L1, TP53, and TAP. As a basic transcriptional regulator, HNRPUL1 represses basic transcription driven by various virus and cellular promoters. In association with BRD7, HNRPUL1 activates glucocorticoid-responsive promoter transcription in the absence of ligand-stimulation. HNRPUL1 might play an important role in nucleocytoplasmic mRNA processing and transport (2). Due to alternative splicing, five different isoform of HNRPUL1 exist.

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC

稀释方法

WB~~1:1000~10000 IHC~~1:250~500

别名

Heterogeneous nuclear ribonucleoprotein U-like protein 1, Adenovirus early region 1B-associated protein 5, E1B-55 kDa-associated protein 5, E1B-AP5, HNRNPUL1, E1BAP5, HNRPUL1

图像

A. Western blot analysis on HeLa cell lysate using anti- HNRPUL1 RabMAb (Cat. AMM05387G), dilution 1:50,000.

B. Immunofluirescent staining of HeLa cells using anti-HNRPUL1 RabMAb (Cat. AMM05387G)

C. Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-HNRPUL1 RabMAb (Cat. AMM05387G)

说明书

数量

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