全部产品分类
品牌 |
Leading Biology | 货号 |
APR16167G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GM130 antibody.
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分子量 |
113086 Da
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
A synthetic peptide corresponding to residues near the N-term of human Golgi Matrix Protein (GM130) was used as a immunogen.
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克隆号 |
EP892Y
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基因ID |
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UniProt ID |
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功能 |
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
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总结 |
Golgi Matrix Protein (GM130) is peripheral cytoplamic protein that is bound to the Golgi membranes. It has been implicated as a maintainer of cis-Golgi structure (1). During mitosis, it regulates the disassembly and reassembly of the Golgi complex. It is also linked to docking and fusion of coatomer (COP I) coated vesicles to the Golgi membrane (2). The COOH-terminal domain of GM130 is highly homologous to Golgi human auto-antigen, golgin-95. GM130 interacts specifically and GTP-dependent manner with Rab1b protein, a regulator of anterograde traffic between ER and Golgi membranes (3). GM130 is also activator of YSK1, an essential player in cell migration.
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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稀释方法 |
WB~~1:50000~100000
IHC~~1:250~500
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别名 |
Golgin subfamily A member 2, 130 kDa cis-Golgi matrix protein, GM130, GM130 autoantigen, Golgin-95, GOLGA2
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图像 |
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说明书 |
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数量 |
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