全部产品分类
品牌 |
Leading Biology | 货号 |
APR11028G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCR8/CKR8 antibody (Loop 2).
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分子量 |
40844 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human, Rat
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靶点 |
A synthetic peptide corresponding to residues in loop2 extracellular domain of human CKR8 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members.
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克隆号 |
E77
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通用名 |
CKRL1, CMKBR8, CMKBRL2
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基因ID |
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UniProt ID |
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功能 |
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
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总结 |
CKR8/CCR8, or C-C chemokine receptor type 8, is a G protein-coupled, seven-transmembrane domain receptor protein. Chemokines are key molecules in directing leukocyte migration toward sites of inflammation. The human C-C chemokine I-309 is a monocyte chemoattractant and inhibits apoptosis in thymic cell lines. It has been found that CKR8/CCR8 is a receptor for chemokines SCYA1/I-309, SCYA4/MIP-1-beta, and SCYA17/TARC (1-3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF
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稀释方法 |
WB~~1:500
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别名 |
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
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图像 |
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说明书 |
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数量 |
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