品牌 |
Leading Biology | 货号 |
APR11547G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Calretinin antibody.
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分子量 |
31540 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
A synthetic peptide corresponding to residues near the N-terminus of human Calretinin was used as an immogen.
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克隆号 |
EPR1798Y
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通用名 |
CAB29
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基因ID |
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UniProt ID |
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功能 |
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
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总结 |
Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to calbindin family. It is mainly found in neuronal tissue, high expressed in auditory neurons. It has been implicated in as a calcium buffer, calcium sensor, and as a regulator of apoptosis (1). Calretinin is considered as a specific marker of mesothelllal cells; it is the only marker that has the utility in distinguishing between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas (2). It is widely used in the panel of makers for distinguishing mesothlioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin and cytokeratin 5/6 (3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~1:500
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别名 |
Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
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图像 |
A. Western blot analysis on (A) fetal brain (B) mouse brain and (C) rat brain lysates using anti-Calretinin RabMAb (Cat. APR11547G), dilution 1:500. |
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说明书 |
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数量 |
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