全部产品分类
品牌 |
Leading Biology | 货号 |
APG01972G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Aquaporin-5 antibody.
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分子量 |
28292 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
A synthetic peptide corresponding to residues in human Aquaporin 5 was used as an immunogen.
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克隆号 |
EPR3747
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基因ID |
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UniProt ID |
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功能 |
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
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总结 |
Aquaporin 5 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions (1). It is expressed in epithelia of lung, cornea, and various secretory glands; sites where extracellular osmolality is known to fluctuate (2). Expression of Aquaporin 5 may have pathophysiological implications attributed to a dysfunctional water regulation by Aquaporin 5such as endolymphatic hydrops (i.e. in Meniere's disease) or sensorineural hearing loss (i.e. in Sj鰃ren's syndrome) (3). Up-regulation of Aquaporin 5 may be involved in differentiation of human gastric cancer cells (4).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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稀释方法 |
WB~~1:1000~10000
IHC~~1:100~250
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别名 |
Aquaporin-5, AQP-5, AQP5
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图像 |
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说明书 |
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数量 |
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