全部产品分类
品牌 |
Leading Biology | 货号 |
AMM00017G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Periostin Antibody (Clone: Stiny-3).
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分子量 |
93314 Da
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi.
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Periostin
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克隆号 |
Clone: Stiny-3
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亚型 |
Mouse IgG2bκ
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通用名 |
OSF2
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基因ID |
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UniProt ID |
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功能 |
Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
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总结 |
Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor β1 (TGF-β1) and bone morphogenetic protein 2 (BMP-2). Abnormal expression of Periostin is also linked to angiogenesis and metastasis in epithelial tumors.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
E
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说明书 |
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数量 |
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