品牌 |
Leading Biology | 货号 |
AMM02637G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P16 (Mouse and Human) Antibody.
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分子量 |
16533 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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克隆号 |
1E12E10
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亚型 |
IgG1
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通用名 |
CDKN2, MTS1
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基因ID |
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UniProt ID |
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功能 |
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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稀释方法 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
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图像 |
Figure 1: Western blot analysis using P16 mouse mAb against truncated P16 recombinant protein.
Figure 2: Immunohistochemical analysis of paraffin-embedded rat liver tissue (A), human brain tumor (B), breast cancer (C), esophageal epithelium tissue (D), mouse brain tissue (E) and stomach tisue (F), showing nuclear localization using P16 mouse mAb with DAB staining. |
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说明书 |
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数量 |
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