品牌 |
Leading Biology | 货号 |
AMM02592G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Synaptobrevin (VAMP) Antibody.
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分子量 |
16 KDa
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宿主 |
Mouse
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种属反应性 |
Bovine, Human, Hamster, Mouse, Pig, Rat, Rabbit
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靶点 |
Synaptic immunoprecipitate (crude) from human brain.
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克隆号 |
SP10
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亚型 |
IgM
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基因ID |
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UniProt ID |
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总结 |
Synaptobrevin (aka VAMP) is an integral membrane protein ofsynaptic vesicles that plays a major role in the formation of larger SNARE complexes, alongwith SNAP-25 and syntaxin. Synaptobrevin hasbeen shown to be essential for two fastsynapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter releaseand fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004).Decreased levels of synaptobrevin in human hippocampus and cortex have been correlatedwith cognitive defects in Alzheimer’s disease (Sze et al., 2000)
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~ 1:1000
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图像 |
Western blot of rat brain lysate showing specific immunolabelingof the ~ 16k synaptobrevin protein. |
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说明书 |
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数量 |
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