> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Proteinase Inhibitor 9 (PI-9) Antibody (Clone PI9-17)品牌 |
Leading Biology | 货号 |
AMM00006G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Proteinase Inhibitor 9 (PI-9) Antibody (Clone PI9-17).
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分子量 |
42404 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
PI9
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克隆号 |
PI9-17
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亚型 |
Mouse IgG1
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通用名 |
PI9
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基因ID |
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UniProt ID |
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功能 |
Granzyme B inhibitor.
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总结 |
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
Western blot analysis of recombinant PI9: Lane 1: 2 μg;Lane 2: 5 μg; Lane 3: 10 μg |
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说明书 |
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数量 |
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