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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > CDH5 Antibody

CDH5 Antibody

货号 货期 规格 / 价格 询价
AMM03091G 100 μl / ¥5450

CDH5 Antibody

品牌

Leading Biology

货号

AMM03091G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH5 Antibody.

分子量

87.5kDa

细胞定位

Antigen Cellular Localization: Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions

宿主

Mouse

种属反应性

Human, Mouse

克隆号

3D5C7

亚型

IgG1

基因ID

UniProt ID

功能

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, FC, E

稀释方法

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

图像

Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng);

Figure 1: Western blot analysis using CDH5 mAb against human CDH5 recombinant protein. (Expected MW is 47.6 kDa)

Figure 2: Western blot analysis using CDH5 mouse mAb against HUVE-12 (1), A549 (2), NIH3T3 (4) cell lysate, and Mouse lung (3) tiusse lysate.

说明书

数量

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