品牌 |
Leading Biology | 货号 |
AMM03079G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPN6 Antibody.
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分子量 |
67.6kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
2E9E4
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亚型 |
IgG1
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通用名 |
HCP, PTP1C
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基因ID |
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UniProt ID |
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功能 |
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
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图像 |
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using PTPN6 mAb against human PTPN6 (AA: 243-541) recombinant protein. (Expected MW is 60 kDa)
Figure 3:Western blot analysis using PTPN6 mAb against HEK293 (1) and PTPN6 (AA: 243-541)-hIgGFc transfected HEK293 (2) cell lysate. |
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说明书 |
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数量 |
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