品牌 |
Leading Biology | 货号 |
AMM03036G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ERCC1 Antibody.
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分子量 |
32.6kDa
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Nucleus. Isoform 3: Nucleus.
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
1E5B3
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亚型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
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图像 |
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng);
Figure 2:Western blot analysis using ERCC1 mAb against human ERCC1 (AA: 151-297) recombinant protein. (Expected MW is 42.5 kDa)
Figure 3:Western blot analysis using ERCC1 mAb against HEK293 (1) and ERCC1 (AA: 151-297)-hIgGFc transfected HEK293 (2) cell lysate. |
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说明书 |
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数量 |
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