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MLXIPL Antibody

AMM02957G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
AMM02957G		100 μl / ￥5450

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MLXIPL Antibody

品牌	Leading Biology	货号	AMM02957G
产品分类	Monoclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLXIPL Antibody.
分子量	93.1kDa
细胞定位	Antigen Cellular Localization: Nucleus.
宿主	Mouse
种属反应性	Human
克隆号	5D12D1
亚型	IgG1
通用名	BHLHD14, MIO, WBSCR14
基因ID	51085
UniProt ID	Q9NP71
功能	Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).
总结	This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. ;
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, ICC, E
稀释方法	E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000
图像	Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Figure 1: Western blot analysis using MLXIPL mAb against human MLXIPL recombinant protein. (Expected MW is 41 kDa) Figure 2: Western blot analysis using MLXIPL mAb against HEK293 (1) and MLXIPL (AA: 18-143)-hIgGFc transfected HEK293 (2) cell lysate.
说明书	Product Datasheet Protocol
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